本科生：兽医产科学

（1）2010.09至2014.06，吉林农业科技学院，伟德BETVlCTOR1946，农学学士

（2）2014.09至2017.06，伟德bv国际体育，伟德BETVlCTOR1946临床兽医学，硕士

（3）2017.09至2020.06，伟德bv国际体育，伟德BETVlCTOR1946临床兽医学，博士

（1）2020.07至2022.07，伟德bv国际体育，伟德BETVlCTOR1946，鼎鑫学者，博士后

（2）2020.09至今，伟德bv国际体育，伟德BETVlCTOR1946，唐敖庆青年学者/人才引进副教授，博士生导师

（1）国家自然科学基金委员会，国家自然科学基金青年基金，32102738，瘤胃源嗜麦芽寡养单胞菌致发乳腺炎的机制研究，2022-01-01至2024-12-31，30万元，在研，主持

（2）伟德bv国际体育人才引进科研启动基金，2023-01-01至2024-12-31，30万，在研，主持

（3）吉林省博士后留吉资助，2023-01-01至2024-12-31，8万，在研，主持

（4）吉林省教育厅，吉林省教育厅科研项目，JJKH20231201KJ，胆汁酸抗金葡菌诱导小鼠乳腺炎的作用及机制研究，2.5万元，2022-10-31至2024-12-31，在研，主持

（5）中国博士后科学基金委员会，中国博士后科学基金面上项目，2020M681045，肠源性寡养单胞菌诱发乳腺炎的分子机制研究，2020-11至2022-07，8万元，结题，主持

（6）中国博士后科学基金委员会，2020TQ0120，中国博士后科学基金第2批特别资助（站前），基于乳腺炎探究“肠-乳轴”及其分子机制，2020-08至2022-07，18万元，结题，主持

1. Hu X, Guo J, Zhao C, Jiang P, Maimai T, Yanyi L, Cao Y, Fu Y, Zhang N. The gut microbiota contributes to the development of Staphylococcus aureus-induced mastitis in mice. ISME J. 2020 Jul;14(7):1897-1910.

2. Hu X, He Z, Zhao C, He Y, Qiu M, Xiang K, Zhang N, Fu Y. Gut/rumen-mammary gland axis in mastitis: Gut/rumen microbiota-mediated "gastroenterogenic mastitis" J Adv Res. 2024 Jan:55:159-171.

3. He Z, Zhao C, He Y, Liu Z, Fan G, Zhu K, Wang Y, Zhang N, Fu Y,Hu X. Enterogenic Stenotrophomonas maltophilia migrates to the mammary gland to induce mastitis by activating the calcium-ROS-AMPK-mTOR-autophagy pathway. J Anim Sci Biotechnol. 2023 Dec 20;14(1):157.

4. Zhao C, Wu K, Hao H, Zhao Y, Bao L, Qiu M, He Y, He Z, Zhang N,Hu X, Fu Y. Gut microbiota-mediated secondary bile acid alleviates Staphylococcus aureus-induced mastitis through the TGR5-cAMP-PKA-NF-κB/NLRP3 pathways in mice.

   NPJ Biofilms Microbiomes. 2023 Feb 8;9(1):8.

5. Zhao C, Bao L, Zhao Y, Wu K, Qiu M, Feng L, Zhang N,Hu X, Fu Y.

   A fiber-enriched diet alleviates Staphylococcus aureus-induced mastitis by activating the HDAC3-mediated antimicrobial program in macrophages via butyrate production in mice. PLoS Pathog. 2023 Jan 19;19(1): e1011108.

6. He Z, Li W, Yuan W, He Y, Xu J, Yuan C, Zhao C, Zhang N, Fu Y,Hu X.

   Lactobacillus reuteri inhibits Staphylococcus aureus-induced mastitis by regulating oxytocin releasing and gut microbiota in mice.

   FASEB J. 2024 Jan 31;38(2): e23383.

7. Zhao C,Hu X, Qiu M, Bao L, Wu K, Meng X, Zhao Y, Feng L, Duan S, He Y, Zhang N, Fu Y. Sialic acid exacerbates gut dysbiosis-associated mastitis through the microbiota-gut-mammary axis by fueling gut microbiota disruption. Microbiome. 2023 Apr 17;11(1):78

8. Zhao C,Hu X, Bao L, Wu K, Zhao Y, Xiang K, Li S, Wang Y, Qiu M, Feng L, Meng X, Zhang N, Fu Y. Gut dysbiosis induces the development of mastitis through a reduction in host anti-inflammatory enzyme activity by endotoxemia. Microbiome. 2022 Dec 1;10(1):205.

9. Hu X, Li S, Mu R, Guo J, Zhao C, Cao Y, Zhang N, Fu Y. The Rumen Microbiota Contributes to the Development of Mastitis in Dairy Cows. Microbiol Spectr. 2022 Feb 23;10(1): e0251221.

Zhao C, Wu K, Bao L, Chen L, Feng L, Liu Z, Wang Y, Fu Y, Zhang N,Hu X. Kynurenic acid protects against mastitis in mice by ameliorating inflammatory responses and enhancing blood-milk barrier integrity. Mol Immunol.

（1）牛主要繁殖障碍防治技术研发与应用，吉林省科学技术进步一等奖

中国兽医协会牛羊诊疗分会副秘书长、中国畜牧兽医学会高级会员，Animals and Zoonoses

青年编委。